Unit Three
We are introduced to Mike Smith, the sixteen-year-old son of Mr. and Mrs. Smith. Mike is diagnosed with osteosarcoma, a type of bone cancer that often affects teenagers. Mike’s treatments put him into remission; in order to remove all of the cancerous tissue, he had to have most of his arm amputated and he needs a prosthesis. Through this case, you will explore the diagnostic process used to determine the presence of cancerous cells, the risk factors and prevention of cancer, rehabilitation after disease or injury, and the design process for new medications, prosthetics, and nanotechnology.
We are introduced to Mike Smith, the sixteen-year-old son of Mr. and Mrs. Smith. Mike is diagnosed with osteosarcoma, a type of bone cancer that often affects teenagers. Mike’s treatments put him into remission; in order to remove all of the cancerous tissue, he had to have most of his arm amputated and he needs a prosthesis. Through this case, you will explore the diagnostic process used to determine the presence of cancerous cells, the risk factors and prevention of cancer, rehabilitation after disease or injury, and the design process for new medications, prosthetics, and nanotechnology.
STANDARDS:Indicator #3: How to conquer cancer
Webb’s Leveling Standard and Examples
Recall MI 3.1 Display information about cancer case studies on graphic organizers.
Recall MI 3.2 Create a concept map that describes the different uses for various diagnostic imaging technologies.
Skill/Concept MI 3.3 Compare normal cells and cancer cells.
Skill/Concept MI 3.4 Perform a simulated DNA microarray to analyze the gene expression patterns of two patients.
Skill/Concept MI 3.5 Read an article about a potential risk factor that interests them and share it with the class.
Skill/Concept MI 3.6 Create a timeline of cancer screenings they should do throughout their life using Inspiration® software.
Skill/Concept MI 3.7 Create an outline of an article about myoelectric prosthetic limbs.
Skill/Concept MI 3.8 Complete an alignment to arrange DNA sequences side-by-side to locate any base pair differences between
different individuals.
Skill/Concept MI 3.9 Determine how many cuts are necessary to cut a 10 cm x 1 cm strip of paper in half before the paper is approximately ten nanometers long.
Skill/Concept MI 3.10 Summarize an article pertaining to the application of nanotechnology in medicine.
Strategic Thinking MI 3.11 Use statistical analysis to determine the similarity between gene expression patterns of three patients.
Strategic Thinking MI 3.12 Complete a skin cancer risk questionnaire and evaluate which risks are in their control.
Strategic Thinking MI 3.13 Perform marker analysis to determine the presence of a genetic mutation associated with breast cancer.
Strategic Thinking MI 3.14 Create a mock interview with a virologist either working to develop a new vaccine or drug for a virus
associated with cancer.
Strategic Thinking MI 3.15 Write journal entries or a blog describing the experiences of teenagers undergoing cancer treatments.
Strategic Thinking MI 3.16 Design and create a simple model of an arm that is able to pick-up an empty Styrofoam cup.
Strategic Thinking MI 3.17 Complete a laboratory investigation using data acquisition software and probes to explore biofeedback
therapy.
Strategic Thinking MI 3.18 Use patients’ SNP profiles to predict how they will respond to particular medicines.
Extended Thinking MI 3.19 Use proper laboratory techniques to design and conduct an experiment to test the effectiveness of various
sunscreens or types of cloth against UV light using UV sensitive yeast cells.
Extended Thinking MI 3.20 Design an experiment to test the effect of relaxation techniques on their heart rate, respiration rate, and skin
temperature.
Extended Thinking MI 3.21 Design and present a comprehensive rehabilitation plan for an assigned patient.
Extended Thinking MI 3.22 Research and present cases of human abuse that lead to the regulations governing clinical trials.
Extended Thinking MI 3.23 Develop and present a clinical trial proposal to test the safety and efficacy of a nanotechnology-based cancer
treatment for an assigned patient.
Webb’s Leveling Standard and Examples
Recall MI 3.1 Display information about cancer case studies on graphic organizers.
Recall MI 3.2 Create a concept map that describes the different uses for various diagnostic imaging technologies.
Skill/Concept MI 3.3 Compare normal cells and cancer cells.
Skill/Concept MI 3.4 Perform a simulated DNA microarray to analyze the gene expression patterns of two patients.
Skill/Concept MI 3.5 Read an article about a potential risk factor that interests them and share it with the class.
Skill/Concept MI 3.6 Create a timeline of cancer screenings they should do throughout their life using Inspiration® software.
Skill/Concept MI 3.7 Create an outline of an article about myoelectric prosthetic limbs.
Skill/Concept MI 3.8 Complete an alignment to arrange DNA sequences side-by-side to locate any base pair differences between
different individuals.
Skill/Concept MI 3.9 Determine how many cuts are necessary to cut a 10 cm x 1 cm strip of paper in half before the paper is approximately ten nanometers long.
Skill/Concept MI 3.10 Summarize an article pertaining to the application of nanotechnology in medicine.
Strategic Thinking MI 3.11 Use statistical analysis to determine the similarity between gene expression patterns of three patients.
Strategic Thinking MI 3.12 Complete a skin cancer risk questionnaire and evaluate which risks are in their control.
Strategic Thinking MI 3.13 Perform marker analysis to determine the presence of a genetic mutation associated with breast cancer.
Strategic Thinking MI 3.14 Create a mock interview with a virologist either working to develop a new vaccine or drug for a virus
associated with cancer.
Strategic Thinking MI 3.15 Write journal entries or a blog describing the experiences of teenagers undergoing cancer treatments.
Strategic Thinking MI 3.16 Design and create a simple model of an arm that is able to pick-up an empty Styrofoam cup.
Strategic Thinking MI 3.17 Complete a laboratory investigation using data acquisition software and probes to explore biofeedback
therapy.
Strategic Thinking MI 3.18 Use patients’ SNP profiles to predict how they will respond to particular medicines.
Extended Thinking MI 3.19 Use proper laboratory techniques to design and conduct an experiment to test the effectiveness of various
sunscreens or types of cloth against UV light using UV sensitive yeast cells.
Extended Thinking MI 3.20 Design an experiment to test the effect of relaxation techniques on their heart rate, respiration rate, and skin
temperature.
Extended Thinking MI 3.21 Design and present a comprehensive rehabilitation plan for an assigned patient.
Extended Thinking MI 3.22 Research and present cases of human abuse that lead to the regulations governing clinical trials.
Extended Thinking MI 3.23 Develop and present a clinical trial proposal to test the safety and efficacy of a nanotechnology-based cancer
treatment for an assigned patient.